Cyclic di-UMP is a pyrimidine-containing cyclic dinucleotide (CDN). It is produced by bacterial cGAS/DncV-like nucleotidyltransferases (CD-NTases), such as LpCdnE02 from L. pneumophila, and binds to cGAS, in the apo or dsDNA-bound forms, with reduced affinity compared to 23-cGAMP (Item No. 19887) or 33-cGAMP (Item No. 17966). Cyclic di-UMP is intended for use as a negative control for cyclic di-GMP signaling.
Cyclic di-UMP is a pyrimidine-containing cyclic dinucleotide (CDN). It is produced by bacterial cGAS/DncV-like nucleotidyltransferases (CD-NTases), such as LpCdnE02 from L. pneumophila, and binds to cGAS, in the apo or dsDNA-bound forms, with reduced affinity compared to 23-cGAMP (Item No. 19887) or 33-cGAMP (Item No. 17966). Cyclic di-UMP is intended for use as a negative control for cyclic di-GMP signaling.
Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.