13--OxoODE--d-3-

13-OxoODE-d3 contains three deuterium atoms at the 9, 10, and 12 positions. It is intended for use as an internal standard for the quantification of 13-OxoODE by GC- or LC-mass spectrometry. 13-oxoODE is produced from 13-HODE by a NAD+-dependent dehydrogenase present in rat colonic mucosa. 13-OxoODE stimulates cell proliferation when instilled intrarectally in rats. 13-OxoODE has also been detected in preparations of rabbit reticulocyte plasma and mitochondrial membranes, mostly esterified to phospholipids. Production of 13-oxoODE is putatively linked to the maturation of reticulocytes to erythrocytes...