Quillaic acid is a triterpene saponin that has been found in Q. saponaria bark and has diverse biological activities. It is cytotoxic to SNU-1 and KATO III gastric cancer cells (IC50s = 13.6 and 67 µM, respectively). Quillaic acid induces hot plate analgesia in mice (ED50 = 20.7 mg/kg). It reduces ear edema induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) or phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice when administered topically at doses of 0.7 and 1.6 mg/ear, respectively.
Quillaic acid is a triterpene saponin that has been found in Q. saponaria bark and has diverse biological activities. It is cytotoxic to SNU-1 and KATO III gastric cancer cells (IC50s = 13.6 and 67 µM, respectively). Quillaic acid induces hot plate analgesia in mice (ED50 = 20.7 mg/kg). It reduces ear edema induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) or phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice when administered topically at doses of 0.7 and 1.6 mg/ear, respectively.
Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.