PKUMDL-LC--101-D04
Cayman Chemical
SKU / CAT#: 28966-5MG
$32000
usd
$64.00/mg
28966-5MG

PKUMDL-LC--101-D04

Cayman Chemical Company, Inc.
$32000
usd
$64.00/mg
Available
SHIPS Jan 12th
Available
SHIPS Jan 12th
SKU
Unit size / Options
Availability
Price
No products found
Description
PKUMDL-LC-101-D04 is an allosteric activator of glutathione peroxidase 4 (GPX4). It increases GPX4 activity to 150% of control levels when used at a concentration of 20 μM in a cell-free assay and at 61 μM in wild-type, but not Gpx4-/-, mouse embryonic fibroblast (MEF) extracts. PKUMDL-LC-101-D04 (200 μM) also reduces cholesterol hydroperoxide-induced MEF death.
PKUMDL-LC-101-D04 is an allosteric activator of glutathione peroxidase 4 (GPX4). It increases GPX4 activity to 150% of control levels when used at a concentration of 20 μM in a cell-free assay and at 61 μM in wild-type, but not Gpx4-/-, mouse embryonic fibroblast (MEF) extracts. PKUMDL-LC-101-D04 (200 μM) also reduces cholesterol hydroperoxide-induced MEF death.
Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
Technical Documents
Datasheet (1)
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
Science SamplesWe’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.

Join Our List

mail
Subscribe to the Scoop blog and get the latest updates on life in the lab.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Related Blog Articles
Related Blog Articles