(+)-Taxifolin is a flavonol with antioxidant activity. It increases cell viability of FeCl2 and H2O2-treated bone marrow-derived mesenchymal stem cells (bmMSCs) when used at concentrations ranging from 1 to 100 µg/ml. It also scavenges PTIO radicals in a pH-dependent manner with lower concentrations needed at higher pH (IC50s = 2.6-0.4 mM for pH 5-9, respectively). (+)-Taxifolin protects against H2O2- and xanthine/xanthine oxidase-induced oxidative injury in primary cultured rat cortical cells (IC50 = 7.8 µg/ml) and inhibits lipid peroxidation in rat brain homogenates (IC50 = 1.02 µg/ml).
(+)-Taxifolin is a flavonol with antioxidant activity. It increases cell viability of FeCl2 and H2O2-treated bone marrow-derived mesenchymal stem cells (bmMSCs) when used at concentrations ranging from 1 to 100 µg/ml. It also scavenges PTIO radicals in a pH-dependent manner with lower concentrations needed at higher pH (IC50s = 2.6-0.4 mM for pH 5-9, respectively). (+)-Taxifolin protects against H2O2- and xanthine/xanthine oxidase-induced oxidative injury in primary cultured rat cortical cells (IC50 = 7.8 µg/ml) and inhibits lipid peroxidation in rat brain homogenates (IC50 = 1.02 µg/ml).
Shipping & Handling
Shipped In
Wet ice in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
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