Ferrostatin-1 is a ferroptosis inhibitor. It inhibits cell death induced by the ferroptosis inducers erastin (Item No. 17754; EC50 = 60 nM) and RSL3, but not by hydrogen peroxide, rotenone, or staurosporine, in HT-1080 cells when used at a concentration of 0.5 μM. Ferrostatin-1 (0.5 μM) inhibits erastin-induced production of reactive oxygen species (ROS) and lipid peroxidation in HT-1080 cells. It increases cell survival in cell-based models of Huntingtons disease, periventricular leukomalacia, and kidney proximal tubule damage in a concentration-dependent manner. Ferrostatin-1 (2 μM) inhibits...
Ferrostatin-1 is a ferroptosis inhibitor. It inhibits cell death induced by the ferroptosis inducers erastin (Item No. 17754; EC50 = 60 nM) and RSL3, but not by hydrogen peroxide, rotenone, or staurosporine, in HT-1080 cells when used at a concentration of 0.5 μM. Ferrostatin-1 (0.5 μM) inhibits erastin-induced production of reactive oxygen species (ROS) and lipid peroxidation in HT-1080 cells. It increases cell survival in cell-based models of Huntingtons disease, periventricular leukomalacia, and kidney proximal tubule damage in a concentration-dependent manner. Ferrostatin-1 (2 μM) inhibits...
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Room Temperature in continental US; may vary elsewhere
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Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
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