Y--27632-(hydro-chloride)

Name: Y--27632-(hydro-chloride)
Price: 584.00 USD
Availability: InStock

Cayman Chemical Company, Inc.

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SKU / CAT#: 10005583-50MG

MPN: 10005583

^$584⁰⁰

usd

^$11.68/mg

Available

SHIPS Dec 26th

Available

SHIPS Dec 26th

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Description

Y-27632 is a potent, ATP-competitive inhibitor of ROCKs including p160ROCK (Ki = 140 nM) and ROCK2 (IC50 = 800 nM). It also inhibits PRK2 with an IC50 value of 600 nM. One-hour treatment with 10 µM Y-27632 blocks apoptosis of dissociated cultured human embryonic stem cells, increasing cloning efficiency by 25% and sustaining survival up to 30 passages.

Shipping & Handling

Shipped In

Room Temperature in continental US; may vary elsewhere

Safety & Storage

Storage Temperature

-20°C

Safety Statement

WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Regulatory & Compliance

Technical Documents

Datasheet (1)

TGtRQ10005583.pdf

MSDS (1)

nspBD10005583m.pdf