Anti-Nerve Growth Factor Receptor Antibody [IHC637]

Primary

Monoclonal

Storing antibodies at various temperatures (up to 40°C) for one week does not affect their activity. As a precautionary measure, we ship all products in insulated packaging with cold packs to provide extra temperature stability in transit. The cold packs may be thawed when you receive the shipment, please be assured that this is normal and your product(s) are safe to use. Once you have received your product(s), please follow the storage instructions on the datasheet(s).

Canada

ELISA, IHC

IHC637

Nerve Growth Factor Receptor

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Mouse

IgG1

Human

Monoclonal

Unconjugated

IHC: 1:100 - 1:200.

Nerve Growth Factor Receptor

Breast

Concentrated antibody is supplied in Tris Buffered Saline, pH 7.3 - 7.7, with 1% Bovine Serum Albumin and < 0.1% Sodium Azide. <br></br>Prediluted antibody is supplied Ready-To-Use in Antibody Diluent Buffer.

Concentrated antibody is available in either 100µl or 1ml sizes while prediluted antibody is available only in the 7ml size. <br></br>Nerve Growth Factor Receptor positive control slides are also available in packs of three.

Nerve Growth Factor Receptor (NGFR), also known as p75, P-75NTR or CD271, is a neurotrophin receptor belonging to the tumor necrosis factor receptor family. NGFR is expressed mainly in Schwann cells and neurons, as well as a number of other non-neuronal cell types, and functions during central and peripheral nervous system development to regulate neuronal growth, migration, differentiation, and cell death. Nerve Growth Factor Receptor is also expressed in melanocytes, melanomas, neuroblastomas, pheochromocytomas, neurofibromas, neurotized nevi (type C melanocytes), and other neural crest cell or tumor derivatives. It has been suggested that NGFR may act as a tumor suppressor indicated in prostate and urothelial cancer, and Anti-Nerve Growth Factor Receptor (NGFR) Antibody is often used in adjunct with S100, to aid in the diagnosis of desmoplastic and neurotrophic malignant melanomas. Anti-NGFR Antibody is also useful as an aid in the diagnosis of breast malignancy, as the antibody labels the myoepithelial cells of breast ducts and intralobular fibroblasts of breast ducts.

This antibody is intended for in vitro diagnostic (IVD) use.<br></br>Anti-Nerve Growth Factor Receptor Antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods.<br></br> Use of this antibody is indicated, subsequent to clinical differential diagnoses of diseases, as an aid in the identification of Nerve Growth Factor Receptor protein within the context of antibody panels, the patient’s clinical history and other diagnostic tests evaluated by a qualified pathologist.