Anti-Microcephalin (F131) Antibody. Rabbit polyclonal antibody to Microcephalin (F131)Microcephalin (MCPH1, BRCT-repeat inhibitor of TERT expression 1, BRIT1) modulates brain size and has been proliferating under strong positive selection for several thousand years, although the nature of the positive selection is poorly understood. Human Microcephalin contains three BRCA1 Cterminal (BRCT) domains and shares 57% identity with its mouse ortholog, the most conserved regions being BRCT domains where there is 80% identity. Pre-dominant expression of human Microcephalin is observed in fetal brain,...
Anti-Microcephalin (F131) Antibody. Rabbit polyclonal antibody to Microcephalin (F131)Microcephalin (MCPH1, BRCT-repeat inhibitor of TERT expression 1, BRIT1) modulates brain size and has been proliferating under strong positive selection for several thousand years, although the nature of the positive selection is poorly understood. Human Microcephalin contains three BRCA1 Cterminal (BRCT) domains and shares 57% identity with its mouse ortholog, the most conserved regions being BRCT domains where there is 80% identity. Pre-dominant expression of human Microcephalin is observed in fetal brain,...
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Shipped In
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Safety & Storage
Storage Temperature
Refer to product data sheet for more information.
Safety Statement
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Regulatory & Compliance
Specifications
CLASS
Primary
SUBCLASS
Polyclonal
SHIPPING NOTES
Storing antibodies at various temperatures (up to 40°C) for one week does not affect their activity. As a precautionary measure, we ship all products in insulated packaging with cold packs to provide extra temperature stability in transit. The cold packs may be thawed when you receive the shipment, please be assured that this is normal and your product(s) are safe to use. Once you have received your product(s), please follow the storage instructions on the datasheet(s).
COUNTRY OF ORIGIN
China
APPLICATION
WB, IHC
TARGET ORGANS
Microcephalin
*USAGE / SAFETY STATEMENT
This product is for research use only. It is not intended for diagnostic or therapeutic use.
PURITY
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
PHYSICAL FORM
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
MWCO (kDa)
~ 95 kDa
HOST SPECIES
Rabbit
REACTIVITY SPECIES
Human, Mouse
CLONALITY
Polyclonal
CONJUGATION/TAG
Unconjugated
IMMUNOGEN
Synthetic peptide, corresponding to amino acids 100-150 of Human Microcephalin.
SPECIFICITY
Microcephalin (F131) pAb detects endogenous levels of Microcephalin protein.
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Refer to product data sheet for more information.
Safety Statement
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Regulatory & Compliance
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