Anti-Cdk1/Cdc2 (phospho-T14) Antibody. Rabbit polyclonal antibody to Cdk1/Cdc2 (phospho-T14)Cdc2, an evolutionarily conserved serine/threonine-specific protein kinase, is essential in the cell cycle transition from G2 to M phase. Cdc2 is regulated by association with B-type cyclins and by reversible phosophorylation. Cyclin B binding facilitates the phosphorylation of Cdc2 p34 on three regulatory sites: threonine 14, tyrosine 15, and threonine 161. In higher eukaryotes, Cdc2 is negatively regulated by phosphorylation of two residues located in the ATP-binding site, Thr 14 and Tyr 15. Cdc2 is positively...
Anti-Cdk1/Cdc2 (phospho-T14) Antibody. Rabbit polyclonal antibody to Cdk1/Cdc2 (phospho-T14)Cdc2, an evolutionarily conserved serine/threonine-specific protein kinase, is essential in the cell cycle transition from G2 to M phase. Cdc2 is regulated by association with B-type cyclins and by reversible phosophorylation. Cyclin B binding facilitates the phosphorylation of Cdc2 p34 on three regulatory sites: threonine 14, tyrosine 15, and threonine 161. In higher eukaryotes, Cdc2 is negatively regulated by phosphorylation of two residues located in the ATP-binding site, Thr 14 and Tyr 15. Cdc2 is positively...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Refer to product data sheet for more information.
Safety Statement
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Regulatory & Compliance
Specifications
CLASS
Primary
SUBCLASS
Polyclonal
SHIPPING NOTES
Storing antibodies at various temperatures (up to 40°C) for one week does not affect their activity. As a precautionary measure, we ship all products in insulated packaging with cold packs to provide extra temperature stability in transit. The cold packs may be thawed when you receive the shipment, please be assured that this is normal and your product(s) are safe to use. Once you have received your product(s), please follow the storage instructions on the datasheet(s).
COUNTRY OF ORIGIN
China
APPLICATION
WB
TARGET ORGANS
Cdk1
*USAGE / SAFETY STATEMENT
This product is for research use only. It is not intended for diagnostic or therapeutic use.
PURITY
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
PHYSICAL FORM
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
MWCO (kDa)
~ 34 kDa
HOST SPECIES
Rabbit
REACTIVITY SPECIES
Human, Mouse, Rat
CLONALITY
Polyclonal
CONJUGATION/TAG
Unconjugated
IMMUNOGEN
Synthetic phosphopeptide derived from human Cdk1/Cdc2 around the phosphorylation site of Threonine 14.
SPECIFICITY
p-Cdk1/Cdc2 (T14) pAb detects endogenous levels of Cdk1/Cdc2 protein only when phosphorylated at Thr14.
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Refer to product data sheet for more information.
Safety Statement
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Regulatory & Compliance
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