Aurora C1 is a member of the aurora/Ipl1p family of protein kinases that are important regulators of mitosis.2 Aurora C is a novel chromosomal passenger protein that, in coordination with Aurora B, regulates mitotic chromosome dynamics in human cells.3,4 Aurora C may play a role in organizing microtubules relating to the function of the centrosome/spindle pole during mitosis, and is localized to the centrosome from anaphase to cytokinesis.5 The expression of Aurora C is maximum at M phase.5 Aurora C is activated by directly associating with inner centromere protein (INCENP).3 Aurora C is expressed...
Aurora C1 is a member of the aurora/Ipl1p family of protein kinases that are important regulators of mitosis.2 Aurora C is a novel chromosomal passenger protein that, in coordination with Aurora B, regulates mitotic chromosome dynamics in human cells.3,4 Aurora C may play a role in organizing microtubules relating to the function of the centrosome/spindle pole during mitosis, and is localized to the centrosome from anaphase to cytokinesis.5 The expression of Aurora C is maximum at M phase.5 Aurora C is activated by directly associating with inner centromere protein (INCENP).3 Aurora C is expressed...
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Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Protein Kinases
APPLICATION
WB
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with R-Phycoerythrin (PE).
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Hu
IMMUNOGEN
Synthetic peptide derived from an internal region of the human Aurora C (Serine/threonine-protein kinase 13, Serine/threonine kinase AIE2, Aurora/IPL1/Eg2 protein 2, Aurora/IPL1-related kinase 3) protein.
SPECIFIC ACTIVITY
Recognizes human Aurora C protein at ~32kD.
COMMODITY CODE
30021010
HOST
rabbit
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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