DTX3 functions as an E3 ubiquitin ligase. It is regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution:
ELISA: 1:1000-1:5000
Western Blot: 1:200-1:1000
Optimal...
DTX3 functions as an E3 ubiquitin ligase. It is regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution:
ELISA: 1:1000-1:5000
Western Blot: 1:200-1:1000
Optimal...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Ubiquitin Ligases
APPLICATION
E IHC WB
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography.
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Hu Mo
IMMUNOGEN
Fusion protein of human DTX3
SPECIFIC ACTIVITY
Human, Mouse
SWISS PROT#
Q8N9I9
COMMODITY CODE
30021010
HOST
rabbit
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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