CD61 associates with CD51 to form vitronectin receptor, or with CD41 to form the CD41/CD61 complex. The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 complex is implicated in tumor metastasis and adenoviral infection.

Shipping & Handling

Shipped In

Cold Packs

Safety & Storage

Storage Temperature

Store the recombinant CD61 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Safety Statement

This recombinant CD61 antibody is available for research use only.

Regulatory & Compliance

Technical Documents

Datasheet (1)

wCqkDrecombinant-cd61-antibody-pmgp3-1r-v3723

Specifications

CLASS

Primary Antibodies

SUBCLASS

Recombinant Monoclonal

UNIPROT ID

P05106

CLONE NUMBER

PMGP3-1R

*USAGE / SAFETY STATEMENT

This recombinant CD61 antibody is available for research use only.

FORMAT

Purified (Sodium Azide Free)

APPLICATION.1

IHC-P

HOST SPECIES

Rabbit

ISOTYPE

Rabbit IgG, kappa

REACTIVITY SPECIES

Human

CLONALITY

Recombinant Rabbit Monoclonal

PURIFICATION

Protein A affinity

IMMUNOGEN

Human recombinant protein was used as the immunogen for the recombinant CD61 antibody.

STORAGE BUFFER

1 mg/ml in 1X PBS; BSA free, sodium azide free

APPLICATION DETAILS

IHC (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)

APPLICATION NOTES

Titration of the recombinant CD61 antibody may be required due to differences in protocols and secondary/substrate sensitivity.<br><br>1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

LOCALIZATION

Cell surface, cytoplasmic