Integrin beta 3 Antibody / ITGB3 / CD61
SKU / CAT#: V3723SAF-100UG
$49900
usd
$4.99/UG
V3723SAF-100UG

Integrin beta 3 Antibody / ITGB3 / CD61

NSJ Bioreagents
SKU / CAT#: V3723SAF-100UG
MPN: V3723SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS May 5th
Available
SHIPS May 5th
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Description
CD61 associates with CD51 to form vitronectin receptor, or with CD41 to form the CD41/CD61 complex. The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 complex is implicated in tumor metastasis and adenoviral infection.
CD61 associates with CD51 to form vitronectin receptor, or with CD41 to form the CD41/CD61 complex. The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 complex is implicated in tumor metastasis and adenoviral infection.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant CD61 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant CD61 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Specifications
CLASS
Primary Antibodies
SUBCLASS
Recombinant Monoclonal
UNIPROT ID
P05106
CLONE NUMBER
PMGP3-1R
*USAGE / SAFETY STATEMENT
This recombinant CD61 antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
IHC-P
HOST SPECIES
Rabbit
ISOTYPE
Rabbit IgG, kappa
REACTIVITY SPECIES
Human
CLONALITY
Recombinant Rabbit Monoclonal
PURIFICATION
Protein A affinity
IMMUNOGEN
Human recombinant protein was used as the immunogen for the recombinant CD61 antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
IHC (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)
APPLICATION NOTES
Titration of the recombinant CD61 antibody may be required due to differences in protocols and secondary/substrate sensitivity.<br><br>1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
LOCALIZATION
Cell surface, cytoplasmic
Questions & Answers (0)
Citations (0)
IHC testing of FFPE human renal cell carcinoma with CD61 antibody (clone PMGP3-1R). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min followed by cooling at RT for 20 min.
IHC testing of FFPE human renal cell carcinoma with CD61 antibody (clone PMGP3-1R). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min followed by cooling at RT for 20 min.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant CD61 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant CD61 antibody is available for research use only.
Regulatory & Compliance
Badge
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