Mucin and cadherin-like protein (MUCDHL), also known as mu-protocadherin, is a 110kD type I transmembrane protein that is both O- and N-glycosylated. It is a calcium-dependant cell adhesion protein in the cadherin superfamily. MUCDHL is found on intestinal and renal epithelium. Human MUCDHL extracellular domain (ECD) contains four cadherin domains (aa71-459) plus several mucin domains (aa540-645). Alternate splicing creates four isoforms that differ in their mucin domains. In the region used as immunogen, human and mouse MUCDHL share 63% aa sequence identity.
Applications:
Suitable for use in...
Mucin and cadherin-like protein (MUCDHL), also known as mu-protocadherin, is a 110kD type I transmembrane protein that is both O- and N-glycosylated. It is a calcium-dependant cell adhesion protein in the cadherin superfamily. MUCDHL is found on intestinal and renal epithelium. Human MUCDHL extracellular domain (ECD) contains four cadherin domains (aa71-459) plus several mucin domains (aa540-645). Alternate splicing creates four isoforms that differ in their mucin domains. In the region used as immunogen, human and mouse MUCDHL share 63% aa sequence identity.
Applications:
Suitable for use in...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Cadherin
APPLICATION
E
ACCESSION#
NP_068743.2, NP_112554.2
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography.
PHYSICAL FORM
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Hu
IMMUNOGEN
Synthetic peptide corresponding to C-PYDAPGGDDSY, from MUPCDH, at C-terminal (NP_068743.2, NP_112554.2).
SPECIFIC ACTIVITY
Recognizes MUPCDH. Species sequence homology: Human.
COMMODITY CODE
30021010
HOST
goat
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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