MRP1 (Multidrug Resistance-associated Protein 1, ATP-binding Cassette Sub-family C Member 1, Leukotriene C(4) Transporter, LTC4 Transporter, MRP, ABCC1)

Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Western Blot: 0.05-0.2ug/ml, observed in lysates of cell line A549 on ~150kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May...