Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution:
ELISA: 1:128,000
Western Blot: 0.05-0.2ug/ml, observed in lysates of cell line A549 on ~150kD bands
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May...
Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution:
ELISA: 1:128,000
Western Blot: 0.05-0.2ug/ml, observed in lysates of cell line A549 on ~150kD bands
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography.
APPLICATION
E WB
PHYSICAL FORM
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
SUBCLASS
Multi Drug Resistance (MDR)
HOST SPECIES
human
ISOTYPE
IgG
IMMUNOGEN
Synthetic peptide corresponding to C-HQSDLKVDENQKAYY, from human ABCC1, at the internal region of the protein (NP_004987.2, NP_063915.2, NP_063953.2, NP_063954.2, NP_063955.2).
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