MAPKAP Kinase-2 is part of mitogen-activated protein (MAP) kinase family which includes MAP kinase kinase kinase and MAP kinase kinase. Once activated MAP Kinase-2 will in turn regulate the phosphorylation and activation of many substrates including cell surface molecules, cytoskeletal proteins, transcription factors, and protein kinases. MAPKAP Kinase-2 is also known to be a MAP kinase substrate (p38 MAPK ) in addition to phosphorylating low molecular weight heat shock proteins (Hsp27 in humans) and tyrosine hydroxylase.
Applications:
Suitable for use in Western Blot. Other applications not...
MAPKAP Kinase-2 is part of mitogen-activated protein (MAP) kinase family which includes MAP kinase kinase kinase and MAP kinase kinase. Once activated MAP Kinase-2 will in turn regulate the phosphorylation and activation of many substrates including cell surface molecules, cytoskeletal proteins, transcription factors, and protein kinases. MAPKAP Kinase-2 is also known to be a MAP kinase substrate (p38 MAPK ) in addition to phosphorylating low molecular weight heat shock proteins (Hsp27 in humans) and tyrosine hydroxylase.
Applications:
Suitable for use in Western Blot. Other applications not...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Protein Kinases
APPLICATION
WB
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography.
PHYSICAL FORM
Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Hu Mo Rt
IMMUNOGEN
Synthetic non-phosphopeptide corresponding to human MAPKAPK-2 around the phosphorylation site of threonine 334 (P-Q-TP-P-L).
SPECIFIC ACTIVITY
Recognizes human MAPKAP Kinase 2. Species Crossreactivity: mouse, rat.
COMMODITY CODE
30021010
HOST
rabbit
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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