Glutamic acid decarboxylase (GAD) catalyzes the conversion of L-glutamic acid to the inhibitory eurotransmitter gamma-aminobutyric acid (GABA). Two forms of human GAD, GAD65 and GAD67, re-encoded by two separate genes. Human GAD65 cDNA encodes a Mr 65,000 polypeptide, with 85aa residues, whereas human GAD67 encodes a Mr 67,000 polypeptide, with 594aa residues. GAD67 gene consists of 16 exons, spread over more than 45kb of genomic DNA. The AD67 gene contains an additional exon (exon 0) that together with part of exon 1, specifies the 5' ntranslated region of GAD67 mRNA. Human GAD67 shows 65% identity...
Glutamic acid decarboxylase (GAD) catalyzes the conversion of L-glutamic acid to the inhibitory eurotransmitter gamma-aminobutyric acid (GABA). Two forms of human GAD, GAD65 and GAD67, re-encoded by two separate genes. Human GAD65 cDNA encodes a Mr 65,000 polypeptide, with 85aa residues, whereas human GAD67 encodes a Mr 67,000 polypeptide, with 594aa residues. GAD67 gene consists of 16 exons, spread over more than 45kb of genomic DNA. The AD67 gene contains an additional exon (exon 0) that together with part of exon 1, specifies the 5' ntranslated region of GAD67 mRNA. Human GAD67 shows 65% identity...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Enzymes, Decarboxylase
APPLICATION
E WB
ACCESSION#
NP_038473.2, NP_000808.2
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography.
PHYSICAL FORM
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
mouse
ISOTYPE
IgG
CROSS REACTIVITY
Bo Ca Hu Mo Po Rt
IMMUNOGEN
Synthetic peptide corresponding to C-QRTNSLEEKSR, from mouse GAD1, at the internal region of the protein (NP_038473.2, NP_000808.2).
SPECIFIC ACTIVITY
Recognizes mouse GAD1. Species sequence homology: Bovine, canine, human, porcine and rat.
COMMODITY CODE
30021010
HOST
goat
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Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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