GLuR5 (GRIK1, Glutamate Receptor, Ionotropic Kainate 1, Excitatory Amino Acid Receptor 3, EAA3, Glutamate Receptor 5, GluR-5)

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Applications: Suitable for use in ELISA and Western...