GCDFP15 (Prolactin-inducible Protein, Gross Cystic Disease Fluid Protein 15, GCDFP-15, Prolactin-induced Protein, Secretory Actin-binding Protein, SABP, gp17, PIP, GPIP4)

Gross cystic disease of the breast is benign premenopausal disorder in which cysts are a predominant pathological lesion. These cysts appear to be formed from excessive aporcine cystic secretions. This fluid is composed of several glycoproteins including a unique 15kD monomer protein, PIP. Cytosolic analysis of normal tissue specimens from all major organs has demonstrated PIP in aporcine epithelia, lacrimal, ceruminous and Mollus glands and in numerous serous cells of the submandibular, tracheal, bronchial, sublingual and minor salivary glands. PIP and prostate specific antigen are co-expressed...