CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.
Applications:
Suitable for use in Flow Cytometry, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended Dilutions:
Flow...
CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.
Applications:
Suitable for use in Flow Cytometry, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended Dilutions:
Flow...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Monoclonal Antibodies
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by Protein A affinity chromatography from tissue culture supernatant.
APPLICATION
FC IHC WB
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide
SUBCLASS
CD Markers
CLONE NUMBER
10B1966 (HM57)
HOST SPECIES
human
ISOTYPE
IgG1
IMMUNOGEN
Synthetic peptide corresponding to aa202-216 of human CD79a.
ANTIBODY TYPE
Mab
GRADE
Affinity Purified
CROSS REACTIVITY
Bo Eq Gt Gp Hu Mk Mo Po Rb Rt
SPECIFIC ACTIVITY
Recognizes an epitope within the cytoplasmic domain of human CD79a. Species Crossreactivity: mouse, canine, rabbit, equine, porcine, monkey, rat, bovine, guinea pig, Fallow deer, American bison, Red deer, ferret and goat.
COMMODITY CODE
30021010
HOST
mouse
SWISS PROT#
P11912
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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