The ligand for CD28 is CD80 (B7) which is found on activated B cells suggesting a role for CD28 in T and B cell interaction.
Applications:
Suitable for use in Flow Cytometry, T cell proliferation and in cell stimulation studies where it has been suggested that measuring T cell function in HIV infected asymptomatic patients may be an early indicator of AIDS, independent of CD4+ cell counts. Other applications have not been tested.
Recommended Dilutions:
Optimal dilutions to be determined by the researcher.
Hybridoma:
Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and Stability:
Store...
The ligand for CD28 is CD80 (B7) which is found on activated B cells suggesting a role for CD28 in T and B cell interaction.
Applications:
Suitable for use in Flow Cytometry, T cell proliferation and in cell stimulation studies where it has been suggested that measuring T cell function in HIV infected asymptomatic patients may be an early indicator of AIDS, independent of CD4+ cell counts. Other applications have not been tested.
Recommended Dilutions:
Optimal dilutions to be determined by the researcher.
Hybridoma:
Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and Stability:
Store...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Monoclonal Antibodies
SUBCLASS
CD Markers
APPLICATION
FC
CLONE NUMBER
2Q1294 (15E8)
ACCESSION#
NM_006139.1
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by ion exchange chromatography following ammonium sulfate precipitation.
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide and a stabilizer. Labeled with Allophycocyanin (APC).
GRADE
Highly Purified
ANTIBODY TYPE
Mab
HOST SPECIES
human
ISOTYPE
IgG1
CROSS REACTIVITY
Hu
IMMUNOGEN
Human T lymphocytes
SPECIFIC ACTIVITY
Recognizes the 44kD antigen found on a sub-population of T-cells and activated B cells. These CD28+ CD8 cells are now known to be cytotoxic T-cell precursors. Will induce the proliferation of resting T lymphocytes. Does not react with B cells, granulocytes or monocytes. Does not crossreact with canine.
SWISS PROT#
P10747
COMMODITY CODE
30021010
HOST
mouse
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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