CD8 is a 32kD transmembrane glycoprotein expressed as either a CD8alpha/alpha homodimer or CD8alpha/beta heterodimer. It is expressed on the “cytotoxic/suppressor” subpopulation of peripheral T cells. CD8 functions primarily as a co-receptor with MHC Class I-restricted TCR’s in antigen recognition.
Applications:
Suitable for use in Immunohistochemistry and Immunoprecipitation. Other applications not tested.
Recommended Dilutions:
Immunohistochemistry: Frozen sections
Optimal dilutions to be determined by the researcher.
Hybridoma:
X63.653 myeloma cells with spleen cells from Balb/c mice.
Recommended...
CD8 is a 32kD transmembrane glycoprotein expressed as either a CD8alpha/alpha homodimer or CD8alpha/beta heterodimer. It is expressed on the “cytotoxic/suppressor” subpopulation of peripheral T cells. CD8 functions primarily as a co-receptor with MHC Class I-restricted TCR’s in antigen recognition.
Applications:
Suitable for use in Immunohistochemistry and Immunoprecipitation. Other applications not tested.
Recommended Dilutions:
Immunohistochemistry: Frozen sections
Optimal dilutions to be determined by the researcher.
Hybridoma:
X63.653 myeloma cells with spleen cells from Balb/c mice.
Recommended...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Monoclonal Antibodies
SUBCLASS
CD Markers
APPLICATION
IHC IP
CLONE NUMBER
3H860 (LT8)
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by ion exchange chromatography.
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase.
GRADE
Highly Purified
ANTIBODY TYPE
Mab
HOST SPECIES
human
ISOTYPE
IgG1
CROSS REACTIVITY
Hu Mk
IMMUNOGEN
Normal human peripheral blood lymphocytes.
SPECIFIC ACTIVITY
Recognizes the human CD8 cell surface glycoprotein expressed by a subset of peripheral blood T cells which express cytotoxic/suppressor activity. It is also expressed weakly on NK cells. Species Crossreactivity: marmoset, chimpanzee, Cynomolgus monkey, Red-bellied Tamarin
SWISS PROT#
P01732, P10966
COMMODITY CODE
30021010
HOST
mouse
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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