AMPK is a highly conserved heterotrimeric protein kinase found in all eukaryotes. The heterotrimeric complex exists as multiple isoforms and consists of a catalytic alpha subunit, which is stabilized by non-catalytic regulatory beta- and gamma- subunits. AMPK plays a vital role in maintaining cellular energy homeostasis and is activated by rising levels of AMP under conditions of hypoxia, ischemia, exercise, low glucose levels.
AMPK may play an important role in the control of type 2 diabetes and metabolic syndromes. Recent studies suggest that AMPK functions as a suppressor of cell proliferation...
AMPK is a highly conserved heterotrimeric protein kinase found in all eukaryotes. The heterotrimeric complex exists as multiple isoforms and consists of a catalytic alpha subunit, which is stabilized by non-catalytic regulatory beta- and gamma- subunits. AMPK plays a vital role in maintaining cellular energy homeostasis and is activated by rising levels of AMP under conditions of hypoxia, ischemia, exercise, low glucose levels.
AMPK may play an important role in the control of type 2 diabetes and metabolic syndromes. Recent studies suggest that AMPK functions as a suppressor of cell proliferation...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Monoclonal Antibodies
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by Protein G affinity chromatography.
APPLICATION
E IF IHC IP WB
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
SUBCLASS
Protein Kinases
CLONE NUMBER
9E22 (34.2)
HOST SPECIES
drosophila
ISOTYPE
IgG2a
IMMUNOGEN
Synthetic peptide corresponding to 29aa within the N-terminal catalytic domain of Drosophila AMPK alpha.
ANTIBODY TYPE
Mab
GRADE
Affinity Purified
CROSS REACTIVITY
Dr Hu Mo Rt
SPECIFIC ACTIVITY
Recognizes both the alpha 1 and the alpha 2 isoforms of Drosophila AMP-activated protein kinase (AMPK). Species Crossreactivity: human, mouse and rat.
COMMODITY CODE
30021010
HOST
mouse
SWISS PROT#
P54646, Q13131
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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