Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
Applications:
Suitable for use in ELISA, Immunohistochemistry and Immunofluorescence. Other applications not tested.
Recommended Dilution:
Immunohistochemistry: 1:200-1:500
Immunofluorescence: 1:50-1:200
Optimal dilutions to be determined by the researcher.
Storage...
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
Applications:
Suitable for use in ELISA, Immunohistochemistry and Immunofluorescence. Other applications not tested.
Recommended Dilution:
Immunohistochemistry: 1:200-1:500
Immunofluorescence: 1:50-1:200
Optimal dilutions to be determined by the researcher.
Storage...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Enzymes, Endonuclease
APPLICATION
E IF IHC
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by Protein G affinity chromatography.
PHYSICAL FORM
Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Hu
IMMUNOGEN
Recombinant protein corresponding to aa82-265 from human crossover junction endonuclease MUS81 protein.
SPECIFIC ACTIVITY
Recognizes human MUS81.
SWISS PROT#
Q96NY9
COMMODITY CODE
30021010
HOST
rabbit
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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