This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.
Applications:
Suitable for use in Western Blot. Other applications not tested.
Recommended...
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.
Applications:
Suitable for use in Western Blot. Other applications not tested.
Recommended...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
GTPase, Rab, Ras, Rho Proteins
APPLICATION
WB
ACCESSION#
NP_001258799
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by affinity chromatography.
PHYSICAL FORM
Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Hu
IMMUNOGEN
Synthetic peptide corresponding to the N-terminal region of human SRGAP2
SPECIFIC ACTIVITY
Recognizes human SRGAP2.
SWISS PROT#
P0DJJ0
COMMODITY CODE
30021010
HOST
rabbit
Questions & Answers (0)
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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