MAPK8IP3 (C-Jun-N-terminal Kinase-interacting Protein 3, Mitogen-activated Protein Kinase 8 Interacting Protein 3)

The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Applications: Suitable for use in Western Blot. Other applications...