Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic...
Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography.
APPLICATION
E IHC WB
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
SUBCLASS
Protease Inhibitors
HOST SPECIES
human
ISOTYPE
IgG
IMMUNOGEN
Recombinant protein corresponding to human SERPINB5.
ACCESSION#
BC020713
ANTIBODY TYPE
Pab
GRADE
Affinity Purified
CROSS REACTIVITY
Hu Mo
SPECIFIC ACTIVITY
Recognizes human SERPINB5. Species Crossreactivity: mouse
COMMODITY CODE
30021010
HOST
rabbit
SWISS PROT#
P36952
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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