This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Applications:
Suitable for use in ELISA, Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry: 1:100-1:300...
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Applications:
Suitable for use in ELISA, Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry: 1:100-1:300...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography.
APPLICATION
E IHC
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
SUBCLASS
Enzymes, Phosphodiesterase
HOST SPECIES
human
ISOTYPE
IgG
IMMUNOGEN
Synthetic peptide corresponding to human PDE5A.
ACCESSION#
NP_001074
ANTIBODY TYPE
Pab
GRADE
Affinity Purified
CROSS REACTIVITY
Hu
SPECIFIC ACTIVITY
Recognizes human PDE5A.
COMMODITY CODE
30021010
HOST
rabbit
SWISS PROT#
O76074
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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