Enghild et al.(1989) found that one ITI member, the pre-alpha-trypsin inhibitor (P-alpha-I), is an approximately 130kD protein that contains the mature ITIH3 heavy chain (HC3) and a 30kD subunit. Bourguignon et al. (1993) stated that P-alpha-I is composed of HC3 covalently linked to bikunin, a Kunitz-type protease inhibitor. They reported that the 885aa H3 precursor protein contains a 10aa propeptide and a 19aa signal peptide. Before or during linkage to bikunin, the C-terminal 238aa are cleaved to produce mature HC3. H3 shares 54% and 41% identity with the H1 and H2 precursor proteins, respectively....
Enghild et al.(1989) found that one ITI member, the pre-alpha-trypsin inhibitor (P-alpha-I), is an approximately 130kD protein that contains the mature ITIH3 heavy chain (HC3) and a 30kD subunit. Bourguignon et al. (1993) stated that P-alpha-I is composed of HC3 covalently linked to bikunin, a Kunitz-type protease inhibitor. They reported that the 885aa H3 precursor protein contains a 10aa propeptide and a 19aa signal peptide. Before or during linkage to bikunin, the C-terminal 238aa are cleaved to produce mature HC3. H3 shares 54% and 41% identity with the H1 and H2 precursor proteins, respectively....
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography.
APPLICATION
E IC IHC WB
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
SUBCLASS
Protease Inhibitors
HOST SPECIES
human
ISOTYPE
IgG
IMMUNOGEN
Recombinant protein corresponding to Pro279-Val467 of human ITIH3 fused to His-Tag and T7-tag at N-terminal expressed in E. coli.
ANTIBODY TYPE
Pab
GRADE
Affinity Purified
CROSS REACTIVITY
Hu
SPECIFIC ACTIVITY
Recognizes human ITIH3.
COMMODITY CODE
30021010
HOST
rabbit
SWISS PROT#
Q06033
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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