KVbeta.3 (Voltage-Gated Potassium Channel Subunit beta-3, K(+) Channel Subunit beta-3, Kv-beta-3, KCNAB3, KCNA3B, KV-beta.3)

The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KVbeta.3 is an accessory K+ channel protein which regulates the activity of the poreforming alpha subunit and alters the functional properties of Kv1.5. KVbeta.3...