HSP27, phosphorylated (S78) (Heat Shock Protein beta-1, HspB1, 28kD Heat Shock Protein, Estrogen-Regulated 24kD Protein, Heat Shock 27kD Protein, HSP 27, Stress-responsive Protein 27, SRP27, HSPB1, HSP27, HSP28)

Hsp27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. Hsp27 synthesis is induced by elevated temperature, as well as estrogen in hormone responsive cells. This protein is involved in stress resistance and actin organization. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSP's and mammalian a-crystalline lens protein. Because of the estrogen-responsive nature of Hsp27, this protein has been studied extensively in human estrogen-responsive...