EZH2 (Enhancer of zeste 2, Enhancer of zeste Homolog 2 (Drosophila), Enhancer of zeste Homolog 2, Enhancer of zeste, Drosophila, Homolog 2, ENX 1, Enx 1h, ENX-1, ENX1, Enx1h, EZH 2, EZH1, EZH2, EZH2_HUMAN, EZH2b, Histone-lysine N-Methyltransferase EZH2, KMT 6, KMT6, KMT6A, Lysine N-Methyltransferase 6, MGC9169, WVS, WVS2)

In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. PcG proteins work in conjunction with the trithorax-group (trxG), which activate homeobox gene expression during embryonic development. ENX-1, a mammalian homolog of the Drosophila gene enhancer of zeste, is a PcG protein that is ubiquitously expressed during early embryogenesis and becomes restricted to the central and peripheral nervous systems and sites of fetal hematopoiesis during later development. In the adult, ENX-1 is restricted to specific...