EGFL4 (C19orf49, EGF-like Domain-Containing Protein 4, EGF-like Protein 4, EGF-like-Domain, multiple 4, EGFL4, Epidermal Growth Factor-like Protein 4, HBV pre-s2 Binding Protein 1, KIAA0817, Megf8, MEGF8, Multiple EGF-like Domain Protein 4, Multiple EGF-like Domains Protein 8, Multiple epidermal Growth Factor-like Domains 8, Multiple epidermal Growth Factor-like Domains Protein 8, SBP1)

EGFL4 (epidermal growth factor-like protein 4), also known as MEGF8 (multiple epidermal growth factor-like domains protein 8) or C19orf49, is a 2,845 amino acid single-pass type I membrane protein. EGFL4 contains 2 CUB domains, 5 EGF-like domains, 12 Kelch repeats, 4 laminin EGF-like domains and 7 PSI domains. Existing as two alternatively spliced isoforms, the gene encoding EGFL4 maps to human chromosome 19q13.2. Chromosome 19 consists of ~63 million bases, makes up over 2% of human genomic DNA, and is recognized for having the greatest gene density of the human chromosomes. It is the genetic...