DAO (ABP, Abp1, ABP1_HUMAN, Amiloride Binding Protein 1 (amine Oxidase (Copper Containing)), Amiloride Binding Protein 1, Amiloride Binding Protein, Amiloride Sensitive amine Oxidase, Amiloride-Binding Protein, Amiloride-Sensitive amine Oxidase [Copper-Containing], Amine Oxidase Copper Domain Containing Protein 1, AOC1, DAO, DAO1, Diamine Oxidase, Histaminase, KAO, Kidney amine Oxidase,)

This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. Applications: Suitable for use in Western Blot, Immunohistochemistry....