HNF4A (Hepatocyte Nuclear Factor 4, alpha, HNF4-alpha, OTTHUMP00000031060, OTTHUMP00000031062, Hepatic Nuclear Factor 4 alpha, Hepatocyte Nuclear Factor 4 alpha, Transcription Factor-14, FLJ39654, HNF4, HNF4a7, HNF4a8, HNF4a9, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14) (HRP)

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants. Applications: Suitable for use in...