CD4 (T-cell Surface Glycoprotein CD4, T-cell Surface Antigen T4/Leu-3) (Biotin)

CD4, also known as T4, is a 55kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. This antibody binds to the D3 domain of CD4 and does not block HIV binding. Applications: Suitable for use in Western Blot. Other applications...