C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. The collagen like regions of C1q interact with the Ca(2+) dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Applications:
Suitable for use in Western Blot. Other applications not...
C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. The collagen like regions of C1q interact with the Ca(2+) dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Applications:
Suitable for use in Western Blot. Other applications not...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by Protein A affinity chromatography.
APPLICATION
WB
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
SUBCLASS
Complement
HOST SPECIES
human
ISOTYPE
IgG
IMMUNOGEN
Full length human C1QB, aa1-253 (NP_000482.3).
ACCESSION#
NM_000491, NP_000482.3
ANTIBODY TYPE
Pab
GRADE
Affinity Purified
CROSS REACTIVITY
Hu Mo
SPECIFIC ACTIVITY
Recognizes human C1QB. Species Crossreactivity: mouse.
COMMODITY CODE
30021010
HOST
rabbit
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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