PEX14, ID (PEX14, Peroxisomal membrane protein PEX14, PTS1 receptor-docking protein, Peroxin-14, Peroxisomal membrane anchor protein PEX14) (APC)

This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. Applications: Suitable for use in Western Blot, Flow Cytometry (Not Tested), FLISA Recommended Dilution: FLISA: 1:1,000 Western Blot: 1:100-500 Storage...