Cpn10 Antibody: ATTO 390

Protein A Purified

ISO 9001:2015

Cpn10

Human Cpn10 peptide AA 91-101

Detects ~ 10kDa.

PBS pH7.3, 0.02% sodium azide *Storage buffer may change when conjugated

https://antibodyregistry.org/search.php?q=AB_2704044

Mitochondrion | Mitochondrion Matrix

Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding of polypeptides. Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process (1). Cpn10 has been located in human platelets, but is also present in human maternal serum (2, 3). It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy (4).

1. Velez-Granell C.S., et al. (1994) J of Cell Science. 107(3): 539-549. 2. Morton H., Hegh V., and Clunie G.J.A. (1974) Nature (London) 249: 459-460. 3. Cavanagh A.C., and Morton H. (1994) Eur. J. Biochem. 222: 551-560. 4. Minto M., et al. (1998) Molecular Cell Research. 1403 (2): 151-157.

Cancer | Heat Shock | Cell Signaling | Protein Trafficking | Chaperone Proteins | Cell Signaling | Metabolism | Mitochondrial Metabolism | Mitochondrial Markers

10kDa Chaperonin Antibody, Chaperonin 10 Antibody, Cpn 10 Antibody, EPF Antibody, GROES Antibody, Heat Shock 10kD protein1 Antibody, HSP10 Antibody, HSPE1 Antibody

Polyclonal

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Canada

WB, IHC, ICC/IF, IP, ELISA

https://www.ncbi.nlm.nih.gov/gene/3336

NP_002148.1

Non-hazardous

Non-hazardous

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

1 mg/ml

WB (1:1000), IHC (1:100); optimal dilutions for assays should be determined by the user.

Rabbit

Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | Rabbit | Sheep | African clawed frog (Xenopus laevis)

ATTO 390