Specifications
SHIPPING NOTES
Blue Ice or 4ºC. All orders received in North America by 12:00 PM PST Monday to Thursday will usually be shipped out on the same day. North American customers will typically receive their orders within 1-2 business days. All shipments are F.O.B. from point of shipment, pre-paid and added to the invoice. Freight charges include but not limited to: priority service and packaging materials.Products are shipped with “cold packs” in insulated containers. There is a charge for this packaging and for the shipping costs via FedEx. Please inspect packages immediately upon receipt and inform Labscoop Customer Support of any shortage or damage within 48 hours of receipt. We can only accept returns after we have given prior authorization and issued specific shipping instructions. If a customer wishes to use their own FedEx account number please indicate this on the purchase order or during checkout.
GENE ID
https://www.ncbi.nlm.nih.gov/gene/6794
*USAGE / SAFETY STATEMENT
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
ANTIBODY TYPE
WB (1:250); optimal dilutions for assays should be determined by the user.
PURIFICATION
Peptide Affinity Purified
QUALITY CERTIFICATION / COMPLIANCE
ISO 9001:2015
IMMUNOGEN
A phospho-specific peptide corresponding to residues surrounding Ser428 of human LKB1 (STK11) (AA425-431)
SPECIFICITY
Detects 48.636 kDa.
STORAGE BUFFER
PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
ANTIBODY ID
https://antibodyregistry.org/search.php?q=AB_2708562
CELLUAR LOCALIZATIONS
Nucleus | Cytoplasm
TISSUE SPECIFICITY
Ubiquitously expressed. Strongest expression in testis and fetal liver.
SCIENTIFIC BACKGROUND
LKB1 is a protein-serine/threonine kinase. Phosphorylates and activates AMP-activated kinase (AMPK), AMPK involved in stress responses, lipid and glucose metabolism. Its mutation pattern in human tumours is very characteristic of a tumour suppressor protein.
RESEARCH AREA
Cancer | Cell Cycle | p53 Pathway | Cell Cycle Inhibitors| Cancer | Cancer Metabolism | Cell Signaling | Metabolism | Energy Transfer Pathways
ALTERNATIVE NAMES
hLKB1 antibody, Liver kinase B1 antibody, LKB1 antibody, PJS antibody, Polarization related protein LKB1 antibody, Renal carcinoma antigen NY-REN-19 antibody, Serine/Threonine Kinase 11 antibody, Serine/threonine protein kinase STK11 antibody, Stk11 antibody, STK11_HUMAN antibody