TRPC7 Antibody, Clone N64A/36: Biotin

Monoclonal

Blue Ice or 4ºC. All orders received in North America by 12:00 PM PST Monday to Thursday will usually be shipped out on the same day. North American customers will typically receive their orders within 1-2 business days. All shipments are F.O.B. from point of shipment, pre-paid and added to the invoice. Freight charges include but not limited to: priority service and packaging materials.Products are shipped with “cold packs” in insulated containers. There is a charge for this packaging and for the shipping costs via FedEx. Please inspect packages immediately upon receipt and inform Labscoop Customer Support of any shortage or damage within 48 hours of receipt. We can only accept returns after we have given prior authorization and issued specific shipping instructions. If a customer wishes to use their own FedEx account number please indicate this on the purchase order or during checkout.

Canada

WB, IHC, ICC/IF, IP, AM

https://www.ncbi.nlm.nih.gov/gene/57113

N64A/36 (Formerly sold as S64A-36)

NP_065122.1

Non-hazardous

Non-hazardous

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

1 mg/ml

WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Mouse

IgG1

Human | Mouse | Rat

Biotin

Protein G Purified

ISO 9001:2015

TRPC7

Synthetic peptide amino acids 845-862 of human TRPC7

Detects ~100kDa.

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

https://antibodyregistry.org/search.php?q=AB_2700713

Membrane

Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulation by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway (1). TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure (2).

1. Numaga T., Wakamori M., and Mori Y. (2007) Handb Exp Pharmacol. 179: 143-151. 2. Satoh S., et al. (2007) Mol Cell Biochem. 294(1-2): 205-215.

Neuroscience | Ion Channels | Transient Receptor Potential (TRP) Channels | Cell Signaling

TRP7 Antibody, KNP3 Antibody, TRPM2 Antibody, transient receptor potential cation channel subfamily C member 7 Antibody