Specifications
SHIPPING NOTES
Blue Ice or 4ºC. All orders received in North America by 12:00 PM PST Monday to Thursday will usually be shipped out on the same day. North American customers will typically receive their orders within 1-2 business days. All shipments are F.O.B. from point of shipment, pre-paid and added to the invoice. Freight charges include but not limited to: priority service and packaging materials.Products are shipped with “cold packs” in insulated containers. There is a charge for this packaging and for the shipping costs via FedEx. Please inspect packages immediately upon receipt and inform Labscoop Customer Support of any shortage or damage within 48 hours of receipt. We can only accept returns after we have given prior authorization and issued specific shipping instructions. If a customer wishes to use their own FedEx account number please indicate this on the purchase order or during checkout.
*USAGE / SAFETY STATEMENT
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
ANTIBODY TYPE
WB (1:1000); optimal dilutions for assays should be determined by the user.
REACTIVITY SPECIES
Species Independent
PURIFICATION
Protein G Purified
QUALITY CERTIFICATION / COMPLIANCE
ISO 9001:2015
GENE ALIAS
N-terminal Arginylation
IMMUNOGEN
Synthetic N-terminal arginylated peptide conjugated to KLH
SPECIFICITY
Specific for N-terminal arginine, next to both glutamic acid and aspartic acid. Does not detect internal arginine.
STORAGE BUFFER
PBS pH 7.4, 50% glycerol, 0.09% Sodium azide *Storage buffer may change when conjugated
ANTIBODY ID
https://antibodyregistry.org/search.php?q=AB_2699918
CELLUAR LOCALIZATIONS
Endoplasmic Reticulum
SCIENTIFIC BACKGROUND
Protein arginylation is the post-translational addition of arginine to proteins by arginyltransferase ATE1. Arginylation of proteins has been found to play an essential role in physiological pathways during embryogenesis and adulthood (1). Arginylation has also been shown to regulate cell stress responses, including ER stress, cytosolic misfolded proteins, and heat stress (2).
REFERENCES
1. Saha S. and Kashina A. (2011) Dev Biol. 385(1): 1-8.
2. Deka K., et al. (2016) Cell Death Discov. 2: 16074.
RESEARCH AREA
Cell Signaling | Post-translational Modifications | Arginylation
ALTERNATIVE NAMES
N-terminal Arginine Antibody, N-terminal Arginylation Antibody, N-terminal Arginylated Antibody, N terminal Arginine Antibody, N terminal Arginylation Antibody, N terminal Arginylated Antibody, Amino-terminal Arginine Antibody, Amino-terminal Arginylation Antibody, Amino-terminal Arginylated Antibody, Amino terminal Arginine Antibody, Amino terminal Arginylation Antibody, Amino terminal Arginylated Antibody