NOC4L Antibody
SKU / CAT#: V9358-20UG
$21900
usd$10.95/UG
NOC4L Antibody
NSJ BioreagentsSKU / CAT#: V9358-20UG
MPN: V9358-20UG
$21900
usd$10.95/UG
Available
SHIPS Apr 21st
Available
SHIPS Apr 21st
SKU
Unit size / Options
Availability
Price
No products found
Description
Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]
Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the N°C4L antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This NOC4L antibody is available for research use only.
Regulatory & Compliance
Technical Documents
Datasheet (1)
Specifications
CLASS
Primary Antibodies
*USAGE / SAFETY STATEMENT
This NOC4L antibody is available for research use only.
FORMAT
Purified
SUBCLASS
Monoclonal
UNIPROT ID
Q9BVI4CLONE NUMBER
PCRP-NOC4L-1B2
APPLICATION.1
FACS, IF
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein A/G affinity
IMMUNOGEN
Recombinant full-length human NOC4L protein was used as the immunogen for the NOC4L antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the NOC4L antibody should be determined by the researcher.
LOCALIZATION
Nucleus
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the N°C4L antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This NOC4L antibody is available for research use only.
Regulatory & Compliance
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.Join Our List
Subscribe to the Scoop blog and get the latest updates on life in the lab.
Related Blog Articles
Related Blog Articles