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MSH2 Antibody
SKU / CAT#: V9303SAF-100UG
$49900
usd
$4.99/UG
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V9303SAF-100UG

MSH2 Antibody

NSJ Bioreagents
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SKU / CAT#: V9303SAF-100UG
MPN: V9303SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 3rd
Available
SHIPS Jul 3rd
SKU
Unit size / Options
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Description
Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC). Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation...
Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC). Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the MSH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This MSH2 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
NQBqWmsh2-antibody-msh2-6549r-v9303
Specifications
CLASS
Primary Antibodies
SUBCLASS
Recombinant Monoclonal
UNIPROT ID
IDP43246
CLONE NUMBER
MSH2/6549R
*USAGE / SAFETY STATEMENT
This MSH2 antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
WB, IHC-P
HOST SPECIES
Rabbit
ISOTYPE
Rabbit IgG
REACTIVITY SPECIES
Human
CLONALITY
Recombinant Rabbit Monoclonal
PURIFICATION
Protein A/G affinity
IMMUNOGEN
Recombinant full-length human MSH2 protein was used as the immunogen for the MSH2 antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the MSH2 antibody should be determined by the researcher.
LOCALIZATION
Nuclear
Questions & Answers (0)
Citations (0)
Western blot testing of human HCT-116 cell lysate using MSH2 antibody (clone MSH2/6549R). Expected molecular weight ~105 kDa.
Western blot testing of human HCT-116 cell lysate using MSH2 antibody (clone MSH2/6549R). Expected molecular weight ~105 kDa.
IHC staining of FFPE human colon tissue with MSH2 antibody (clone MSH2/6549R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
+1
IHC staining of FFPE human colon tissue with MSH2 antibody (clone MSH2/6549R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the MSH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This MSH2 antibody is available for research use only.
Regulatory & Compliance
Badge
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