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STAT5A Antibody
SKU / CAT#: V9237SAF-100UG
$49900
usd
$4.99/UG
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V9237SAF-100UG

STAT5A Antibody

NSJ Bioreagents
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SKU / CAT#: V9237SAF-100UG
MPN: V9237SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
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Description
Signal transducer and activator of transcription 5A (Stat5a) and Stat5b, which share 96% homology, undergo receptor tyrosine kinase or G protein-coupled receptor-dependent phosphorylation in response to cytokines or growth factors, and then form homo- or heterodimers that translocate to the nucleus, where they initiate transcription. Activation of Stat5a via IL-2, IL-3, IL-7/ GM-CSF, erythropoietin, thrombopoietin and growth hormones influences proliferation, differentiation and apoptosis in lymphohematopoietic cells. Phosphorylation of Stat5a at Ser127/Ser128 and Ser779 are contigent on ErbB-4-...
Signal transducer and activator of transcription 5A (Stat5a) and Stat5b, which share 96% homology, undergo receptor tyrosine kinase or G protein-coupled receptor-dependent phosphorylation in response to cytokines or growth factors, and then form homo- or heterodimers that translocate to the nucleus, where they initiate transcription. Activation of Stat5a via IL-2, IL-3, IL-7/ GM-CSF, erythropoietin, thrombopoietin and growth hormones influences proliferation, differentiation and apoptosis in lymphohematopoietic cells. Phosphorylation of Stat5a at Ser127/Ser128 and Ser779 are contigent on ErbB-4-...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the STAT5A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This STAT5A antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
hccMFstat5a-antibody-pcrp-stat5a-1a11-v9237
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P42229
CLONE NUMBER
PCRP-STAT5A-1A11
*USAGE / SAFETY STATEMENT
This STAT5A antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
FACS
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein A/G affinity
IMMUNOGEN
STAT5A protein was used as the immunogen for the STAT5A antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
Flow cytometry: 1-2ug/million cells
APPLICATION NOTES
Optimal dilution of the STAT5A antibody should be determined by the researcher.
LOCALIZATION
Cytoplasm, Nucleus
Questions & Answers (0)
Citations (0)
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using STAT5A antibody (clone PCRP-STAT5A-1A11). These results demonstrate the foremost specificity of the PCRP-STAT5A-1A11 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using STAT5A antibody (clone PCRP-STAT5A-1A11). These results demonstrate the foremost specificity of the PCRP-STAT5A-1A11 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
FACS staining of PFA-fixed human HeLa cells with STAT5A antibody (blue, clone PCRP-STAT5A-1A11) and isotype control (red).
SDS-PAGE analysis of purified, BSA-free STAT5A antibody (PCRP-STAT5A-1A11) as confirmation of integrity and purity.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the STAT5A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This STAT5A antibody is available for research use only.
Regulatory & Compliance
Badge
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