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SIRT2 Antibody
SKU / CAT#: V9228-100UG
$49900
usd
$4.99/UG
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V9228-100UG

SIRT2 Antibody

NSJ Bioreagents
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SKU / CAT#: V9228-100UG
MPN: V9228-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
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Description
The silent information regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes, including transcriptional regulation, cell cycle progression, DNA-damage repair and aging. In S. cerevisiae, Sir2p deacetylates histones in a NAD-dependent manner, which regulates silencing at the telomeric, rDNA and silent mating-type loci. Sir2p is the founding member of a large family, designated sirtuins, which contain a conserved catalytic domain. The human homologs, which include SIRT1-7, are divided into four main branches: SIRT1-3 are class...
The silent information regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes, including transcriptional regulation, cell cycle progression, DNA-damage repair and aging. In S. cerevisiae, Sir2p deacetylates histones in a NAD-dependent manner, which regulates silencing at the telomeric, rDNA and silent mating-type loci. Sir2p is the founding member of a large family, designated sirtuins, which contain a conserved catalytic domain. The human homologs, which include SIRT1-7, are divided into four main branches: SIRT1-3 are class...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the Sirtuin 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Sirtuin 2 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
QEUetsirtuin-2-antibody-pcrp-sirt2-1a8-v9228
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
Q8IXJ6
CLONE NUMBER
PCRP-SIRT2-1A8
*USAGE / SAFETY STATEMENT
This Sirtuin 2 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
FACS, IF, WB
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein A/G affinity
IMMUNOGEN
Recombinant full-length human SIRT2/Sirtuin 2 protein was used as the immunogen for the Sirtuin 2 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Western blot: 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the Sirtuin 2 antibody should be determined by the researcher.
LOCALIZATION
Cytoplasm
Questions & Answers (0)
Citations (0)
Immunofluorescent staining of PFA-fixed human HeLa cells using Sirtuin 2 antibody (green, clone PCRP-SIRT2-1A8) and phalloidin (red).
Immunofluorescent staining of PFA-fixed human HeLa cells using Sirtuin 2 antibody (green, clone PCRP-SIRT2-1A8) and phalloidin (red).
Immunofluorescent staining of PFA-fixed U-87 cells using Sirtuin 2 antibody (green, clone PCRP-SIRT2-1A8) and phalloidin (red).
+2
FACS staining of PFA-fixed human MCF-7 cells with Sirtuin 2 antibody (blue, clone PCRP-SIRT2-1A8), and unstained cells (red).
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the Sirtuin 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This Sirtuin 2 antibody is available for research use only.
Regulatory & Compliance
Badge
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