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SMNDC1 Antibody
SKU / CAT#: V9222-100UG
$49900
usd
$4.99/UG
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V9222-100UG

SMNDC1 Antibody

NSJ Bioreagents
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SKU / CAT#: V9222-100UG
MPN: V9222-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 3rd
Available
SHIPS Jul 3rd
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Description
SPF30 (survival of motor neuron-related-splicing factor 30), also known as SMNDC1 (survival motor neuron domain containing 1) or SMNR (SMN-related protein), is an essential splicing factor required for spliceosome assembly that belongs to the SMN family. It contains one Tudor domain with significant similarity to SMN (survival motor neuron) and is expressed in skeletal muscle, pancreas and heart, localizing to Cajal bodies and nuclear speckles. SPF30 plays an important role in spliceosome assembly and directly interacts with five U snRNPs. The loss of SPF30 causes spliceosome assembly to arrest...
SPF30 (survival of motor neuron-related-splicing factor 30), also known as SMNDC1 (survival motor neuron domain containing 1) or SMNR (SMN-related protein), is an essential splicing factor required for spliceosome assembly that belongs to the SMN family. It contains one Tudor domain with significant similarity to SMN (survival motor neuron) and is expressed in skeletal muscle, pancreas and heart, localizing to Cajal bodies and nuclear speckles. SPF30 plays an important role in spliceosome assembly and directly interacts with five U snRNPs. The loss of SPF30 causes spliceosome assembly to arrest...
Shipping & Handling
Shipped In
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Safety & Storage
Storage Temperature
Aliquot the SMNDC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This SMNDC1 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
QGZMVsmndc1-antibody-pcrp-smndc1-1a9-v9222
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
O75940
CLONE NUMBER
PCRP-SMNDC1-1A9
*USAGE / SAFETY STATEMENT
This SMNDC1 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
FACS, IF
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2b
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein A/G affinity
IMMUNOGEN
Recombinant full-length human SMNDC1 protein was used as the immunogen for the SMNDC1 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the SMNDC1 antibody should be determined by the researcher.
LOCALIZATION
Nucleus
Questions & Answers (0)
Citations (0)
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using SMNDC1 antibody (clone PCRP-SMNDC1-1A9). These results demonstrate the foremost specificity of the PCRP-SMNDC1-1A9 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using SMNDC1 antibody (clone PCRP-SMNDC1-1A9). These results demonstrate the foremost specificity of the PCRP-SMNDC1-1A9 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Immunofluorescent staining of PFA-fixed human HeLa cells using SMNDC1 antibody (green, clone PCRP-SMNDC1-1A9) and phalloidin (red).
+1
FACS staining of PFA-fixed human HeLa cells with SMNDC1 antibody (blue, clone PCRP-SMNDC1-1A9), and unstained cells (red).
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the SMNDC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This SMNDC1 antibody is available for research use only.
Regulatory & Compliance
Badge
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