GTF2IRD2 Antibody / GTF2IRD2 alpha
SKU / CAT#: V9214-20UG
$21900
usd
$10.95/UG
V9214-20UG

GTF2IRD2 Antibody / GTF2IRD2 alpha

NSJ Bioreagents
SKU / CAT#: V9214-20UG
MPN: V9214-20UG
$21900
usd
$10.95/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
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Description
The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (also called GTF2IRD2 alpha and GTF2IRD2A) and GTF2IRD2B. Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant...
The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (also called GTF2IRD2 alpha and GTF2IRD2A) and GTF2IRD2B. Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant...
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Safety & Storage
Storage Temperature
Aliquot the GTF2IRD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This GTF2IRD2 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
Q86UP8
CLONE NUMBER
PCRP-GTF2IRD2-1B4
*USAGE / SAFETY STATEMENT
This GTF2IRD2 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
FACS, WB
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2a
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein A/G affinity
IMMUNOGEN
Recombinant full-length human General transcription factor II-I repeat domain-containing protein 2A protein was used as the immunogen for the GTF2IRD2 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Flow cytometry: 1-2ug/million cells,Western blot: 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the GTF2IRD2 antibody should be determined by the researcher.
LOCALIZATION
Nucleus
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Citations (0)
SDS-PAGE analysis of purified, BSA-free GTF2IRD2 antibody (clone PCRP-GTF2IRD2-1B4) as confirmation of integrity and purity.
SDS-PAGE analysis of purified, BSA-free GTF2IRD2 antibody (clone PCRP-GTF2IRD2-1B4) as confirmation of integrity and purity.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using GTF2IRD2 antibody (clone PCRP-GTF2IRD2-1B4). These results demonstrate the foremost specificity of the PCRP-GTF2IRD2-1B4 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
FACS staining of PFA-fixed human HeLa cells with GTF2IRD2 antibody (blue, clone PCRP-GTF2IRD2-1B4), and unstained cells (red).
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the GTF2IRD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This GTF2IRD2 antibody is available for research use only.
Regulatory & Compliance
Badge
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