IRF3 Antibody
SKU / CAT#: V9201-100UG
$49900
usd$4.99/UG
IRF3 Antibody
NSJ BioreagentsSKU / CAT#: V9201-100UG
MPN: V9201-100UG
$49900
usd$4.99/UG
Available
SHIPS Oct 30th
Available
SHIPS Oct 30th
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Description
In the absence of viral infection, IRF3 is maintained as a monomer in an autoinhibited state. Phosphorylation by TBK1 and IKBKE disrupts this autoinhibition leading to the liberation of the DNA-binding and dimerization activities and its nuclear localization where it can activate type I IFN and ISG genes. [UniProt]
In the absence of viral infection, IRF3 is maintained as a monomer in an autoinhibited state. Phosphorylation by TBK1 and IKBKE disrupts this autoinhibition leading to the liberation of the DNA-binding and dimerization activities and its nuclear localization where it can activate type I IFN and ISG genes. [UniProt]
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the IRF3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This IRF3 antibody is available for research use only.
Regulatory & Compliance
Technical Documents
Datasheet (1)
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
Q14653CLONE NUMBER
PCRP-IRF3-6C8
*USAGE / SAFETY STATEMENT
This IRF3 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
FACS, IF, WB
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2b, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein A/G affinity
IMMUNOGEN
Recombinant full-length human IRF3 protein was used as the immunogen for the IRF3 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Western blot: 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the IRF3 antibody should be determined by the researcher.
LOCALIZATION
Cytoplasm, Nucleus
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Citations (0)
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the IRF3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This IRF3 antibody is available for research use only.
Regulatory & Compliance
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